Just Lose It is the first single from Eminem's fifth studio album Encore and was later included on his 2005 compilation album, Curtain Call: The Hits. The song caused controversy as its lyrics and music video parodies Michael Jackson, who was being accused of child molestation at the time.
The song also pokes fun at Beavis/Cornholio, MC Hammer, Madonna and others. It also heavily spoofs Pee-wee Herman, going as far as imitating his signature shout during the chorus and Eminem dressing like him in the video. The song reached number one in the UK, Australia, and New Zealand, and number six in the United States. Despite charting high, the song did not perform as well as his two previous lead singles, "The Real Slim Shady" and "Without Me".